SAR by Oxime-Containing Peptide Libraries: Application to Tsg101 Ligand Optimization

HIV-1 viral assembly requires a direct interaction between a Pro-Thr-Ala-Pro (“PTAP”) motif in the viral protein Gag-p6 and the cellular endosomal sorting factor Tsg101. In an effort to develop competitive inhibitors of this interaction, an SAR study was conducted based on the application of post so...

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Detalhes bibliográficos
Main Authors: Liu, Fa, Stephen, Andrew G., Waheed, Abdul A., Aman, M. Javad, Freed, Eric O., Fisher, Robert J., Burke, Terrence R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2581409/
https://ncbi.nlm.nih.gov/pubmed/18655064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200800281
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