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Oxime-based linker libraries as a general approach for the rapid generation and screening of multidentate inhibitors
The described oxime-based library protocol provides detailed procedures for the linkage of aminooxy functionality with aldehyde building blocks that result in the generation of libraries of multidentate inhibitors. Synthesis of inhibitors for protein tyrosine phosphatases (PTPs) and antagonists dire...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3727389/ https://ncbi.nlm.nih.gov/pubmed/22422315 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2012.007 |
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