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Setting the chaperonin timer: The effects of K(+) and substrate protein on ATP hydrolysis
The effects of potassium ion on the nested allostery of GroEL are due to increases in the affinity for nucleotide. Both positive allosteric transitions, TT-TR and TR-RR, occur at lower [ATP] as [K(+)] is increased. Negative cooperativity in the double-ringed system is also due to an increase in the...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2008
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2580752/ https://ncbi.nlm.nih.gov/pubmed/18988745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0807429105 |
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