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Identifying natural substrates for chaperonins using a sequence-based approach

The Escherichia coli chaperonin machinery, GroEL, assists the folding of a number of proteins. We describe a sequence-based approach to identify the natural substrate proteins (SPs) for GroEL. Our method is based on the hypothesis that natural SPs are those that contain patterns of residues similar...

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Detalles Bibliográficos
Main Authors: Stan, George, Brooks, Bernard R., Lorimer, George H., Thirumalai, D.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2253340/
https://ncbi.nlm.nih.gov/pubmed/15576562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.04933205
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