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The GroEL chaperonin: a protein machine with pistons driven by ATP binding and hydrolysis

In response to the binding of ATP, the two heptameric rings of the GroEL chaperonin protein interact with one another in a negatively cooperative manner. Owing to the helix dipole, the positively charged nitrogen of glycine 88 at the N-terminus of helix D binds to oxygen atoms on the β and γ phospho...

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Detalhes bibliográficos
Publicado no:Philos Trans R Soc Lond B Biol Sci
Main Authors: Lorimer, George H., Fei, Xue, Ye, Xiang
Formato: Artigo
Idioma:Inglês
Publicado em: The Royal Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941174/
https://ncbi.nlm.nih.gov/pubmed/29735733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0179
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