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The GroEL chaperonin: a protein machine with pistons driven by ATP binding and hydrolysis

In response to the binding of ATP, the two heptameric rings of the GroEL chaperonin protein interact with one another in a negatively cooperative manner. Owing to the helix dipole, the positively charged nitrogen of glycine 88 at the N-terminus of helix D binds to oxygen atoms on the β and γ phospho...

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Dades bibliogràfiques
Publicat a:Philos Trans R Soc Lond B Biol Sci
Autors principals: Lorimer, George H., Fei, Xue, Ye, Xiang
Format: Artigo
Idioma:Inglês
Publicat: The Royal Society 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5941174/
https://ncbi.nlm.nih.gov/pubmed/29735733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rstb.2017.0179
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