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Formation and structures of GroEL:GroES(2) chaperonin footballs, the protein-folding functional form

The GroE chaperonins assist substrate protein (SP) folding by cycling through several conformational states. With each cycle the SP is, in turn, captured, unfolded, briefly encapsulated (t(1/2) ∼1 s), and released by the chaperonin complex. The protein-folding functional form is the US-football–shap...

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Detalhes bibliográficos
Main Authors: Fei, Xue, Ye, Xiang, LaRonde, Nicole A., Lorimer, George H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156775/
https://ncbi.nlm.nih.gov/pubmed/25136110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1412922111
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