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YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway
BACKGROUND AND PURPOSE: The aim of this study was to elucidate the mechanism of YC-1{3-(5′-hydroxy methyl-2′-furyl)-1-benzylindazole}-induced human renal carcinoma cells apoptosis and to evaluate the potency of YC-1 in models of tumour growth in mice. EXPERIMENTAL APPROACH: YC-1-mediated apoptosis w...
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Asıl Yazarlar: | , , , , , , , , , |
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Materyal Türü: | Artigo |
Dil: | Inglês |
Baskı/Yayın Bilgisi: |
Nature Publishing Group
2008
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Konular: | |
Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2579664/ https://ncbi.nlm.nih.gov/pubmed/18641674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.292 |
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