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The ROS/JNK/ATF2 pathway mediates selenite-induced leukemia NB4 cell cycle arrest and apoptosis in vitro and in vivo

It has previously been shown that selenite can act as an antitumor agent and inhibit cancer cell growth, although the mechanism responsible for this effect is not well understood. In this study, we have shown that selenite can induce cell cycle arrest and apoptosis in NB4 cells. Selenite treatment o...

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Detalhes bibliográficos
Main Authors: An, J J, Shi, K J, Wei, W, Hua, F Y, Ci, Y L, Jiang, Q, Li, F, Wu, P, Hui, K Y, Yang, Y, Xu, C M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3877548/
https://ncbi.nlm.nih.gov/pubmed/24357804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.475
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