Survivin-2B promotes autophagy by accumulating IKK alpha in the nucleus of selenite-treated NB4 cells

Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others, and the mechanisms are unclear. In this report, we discovered that selenite, an antitumor agent, switched protective autophagy to apoptosis...

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Detalhes bibliográficos
Main Authors: Shi, K, An, J, Shan, L, Jiang, Q, Li, F, Ci, Y, Wu, P, Duan, J, Hui, K, Yang, Y, Xu, C
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3944251/
https://ncbi.nlm.nih.gov/pubmed/24556686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2014.34
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