YC-1 induces apoptosis of human renal carcinoma A498 cells in vitro and in vivo through activation of the JNK pathway

BACKGROUND AND PURPOSE: The aim of this study was to elucidate the mechanism of YC-1{3-(5′-hydroxy methyl-2′-furyl)-1-benzylindazole}-induced human renal carcinoma cells apoptosis and to evaluate the potency of YC-1 in models of tumour growth in mice. EXPERIMENTAL APPROACH: YC-1-mediated apoptosis w...

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Detalhes bibliográficos
Main Authors: Wu, S Y, Pan, S L, Chen, T H, Liao, C H, Huang, D Y, Guh, J H, Chang, Y L, Kuo, S C, Lee, F Y, Teng, C M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2579664/
https://ncbi.nlm.nih.gov/pubmed/18641674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.292
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