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An electrostatic network and long-range regulation of Src kinases
The regulatory mechanism of Src tyrosine kinases includes conformational activation by a change in the catalytic domain tertiary structure and in domain–domain contacts between the catalytic domain and the SH2/SH3 regulatory domains. The kinase is activated when tyrosine phosphorylation occurs on th...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2578809/ https://ncbi.nlm.nih.gov/pubmed/18687871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.037457.108 |
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