Substrate binding to Src: A new perspective on tyrosine kinase substrate recognition from NMR and molecular dynamics

Most signal transduction pathways in humans are regulated by protein kinases through phosphorylation of their protein substrates. Typical eukaryotic protein kinases are of two major types: those that phosphorylate‐specific sequences containing tyrosine (~90 kinases) and those that phosphorylate eith...

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Dettagli Bibliografici
Pubblicato in:Protein Sci
Autori principali: Joshi, Mehul K., Burton, Robert A., Wu, Heng, Lipchik, Andrew M., Craddock, Barbara P., Mo, Huaping, Parker, Laurie L., Miller, W. Todd, Post, Carol Beth
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley & Sons, Inc. 2019
Soggetti:
Accelerated Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954736/
https://ncbi.nlm.nih.gov/pubmed/31697410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3777
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