Substrate binding to Src: A new perspective on tyrosine kinase substrate recognition from NMR and molecular dynamics

Most signal transduction pathways in humans are regulated by protein kinases through phosphorylation of their protein substrates. Typical eukaryotic protein kinases are of two major types: those that phosphorylate‐specific sequences containing tyrosine (~90 kinases) and those that phosphorylate eith...

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Detalhes bibliográficos
Publicado no:Protein Sci
Main Authors: Joshi, Mehul K., Burton, Robert A., Wu, Heng, Lipchik, Andrew M., Craddock, Barbara P., Mo, Huaping, Parker, Laurie L., Miller, W. Todd, Post, Carol Beth
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2019
Assuntos:
Accelerated Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6954736/
https://ncbi.nlm.nih.gov/pubmed/31697410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.3777
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