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An electrostatic network and long-range regulation of Src kinases

The regulatory mechanism of Src tyrosine kinases includes conformational activation by a change in the catalytic domain tertiary structure and in domain–domain contacts between the catalytic domain and the SH2/SH3 regulatory domains. The kinase is activated when tyrosine phosphorylation occurs on th...

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Detalhes bibliográficos
Main Authors: Ozkirimli, Elif, Yadav, Shalini S., Miller, W. Todd, Post, Carol Beth
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2578809/
https://ncbi.nlm.nih.gov/pubmed/18687871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.037457.108
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