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Sex-specific modulation of spinal nociception by α(2)-adrenoceptors: differential regulation by estrogen and testosterone

Sex-related differences in antinociception produced by the activation of α(2)-adrenoceptors (α(2)-ARs) have been reported, however, the precise role of gonadal steroids is still unknown. Hence, we hypothesized that estrogen and testosterone modulate antinociceptive effects of clonidine (an α(2)-AR a...

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Autors principals: Thompson, Analisa D., Angelotti, Timothy, Nag, Subodh, Mokha, Sukhbir S.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577833/
https://ncbi.nlm.nih.gov/pubmed/18434028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.03.008
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