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Activation of the trigeminal α(2)-adrenoceptor produces sex-specific, estrogen dependent thermal antinociception and antihyperalgesia using an operant pain assay in the rat

Higher prevalence of several pain disorders in women and sexual dimorphism in G-protein coupled receptor-induced analgesia have been reported. We have previously shown that α(2)-adrenoceptor-induced antinociception is sex-specific and attenuated by estrogen in the female rat. However, this evidence...

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Detalhes bibliográficos
Publicado no:Behav Brain Res
Main Authors: Nag, Subodh, Mokha, Sukhbir S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4996728/
https://ncbi.nlm.nih.gov/pubmed/27506651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2016.08.012
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