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Sex-specificity and estrogen-dependence of kappa opioid receptor-mediated antinociception and antihyperalgesia
This investigation determined whether activation of the kappa opioid receptor (KOR) in the spinal cord produces estrogen-dependent, sex-specific modulation of acute and inflammation-induced persistent nociception. We demonstrate for the first time that KOR antinociception and gene expression are enh...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2972410/ https://ncbi.nlm.nih.gov/pubmed/20926192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2010.09.018 |
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