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Sex-specificity and estrogen-dependence of kappa opioid receptor-mediated antinociception and antihyperalgesia

This investigation determined whether activation of the kappa opioid receptor (KOR) in the spinal cord produces estrogen-dependent, sex-specific modulation of acute and inflammation-induced persistent nociception. We demonstrate for the first time that KOR antinociception and gene expression are enh...

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Bibliografiske detaljer
Main Authors: Lawson, Kera P., Nag, Subodh, Thompson, Analisa D., Mokha, Sukhbir S.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972410/
https://ncbi.nlm.nih.gov/pubmed/20926192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pain.2010.09.018
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