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Sex-specific modulation of spinal nociception by α(2)-adrenoceptors: differential regulation by estrogen and testosterone
Sex-related differences in antinociception produced by the activation of α(2)-adrenoceptors (α(2)-ARs) have been reported, however, the precise role of gonadal steroids is still unknown. Hence, we hypothesized that estrogen and testosterone modulate antinociceptive effects of clonidine (an α(2)-AR a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577833/ https://ncbi.nlm.nih.gov/pubmed/18434028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2008.03.008 |
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