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Testosterone is essential for α(2)-adrenoceptor-induced antinociception in the trigeminal region of the male rat
Activation of the α(2)-adrenoceptor has been shown to produce antinociception. We have previously shown that the antinociceptive effect of clonidine, an α(2)-adrenoceptor agonist, is sex-specific and is abolished by exogenous estrogen in ovariectomized rats or high level of endogenous estrogen in pr...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2783499/ https://ncbi.nlm.nih.gov/pubmed/19819297 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2009.10.016 |
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