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Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax
A central issue in the control of apoptosis is whether its essential mediators Bax and Bak must be restrained by Bcl-2-like prosurvival relatives to prevent their damaging mitochondria and unleashing apoptosis. The issue is particularly vexed for Bax, which is largely a cytosolic monomer in unstress...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577705/ https://ncbi.nlm.nih.gov/pubmed/18981409 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808691105 |
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