Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranes

The Bcl-2 (B-cell lymphoma 2) protein Bax (Bcl-2 associated X, apoptosis regulator) can commit cells to apoptosis via outer mitochondrial membrane permeabilization. Bax activity is controlled in healthy cells by prosurvival Bcl-2 proteins. C-terminal Bax transmembrane domain interactions were implic...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Andreu-Fernández, Vicente, Sancho, Mónica, Genovés, Ainhoa, Lucendo, Estefanía, Todt, Franziska, Lauterwasser, Joachim, Funk, Kathrin, Jahreis, Günther, Pérez-Payá, Enrique, Mingarro, Ismael, Edlich, Frank, Orzáez, Mar
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2017
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5240701/
https://ncbi.nlm.nih.gov/pubmed/28028215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1612322114
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