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BCL2 and related prosurvival proteins require BAK1 and BAX to affect autophagy

It is widely thought that prosurvival BCL2 family members not only inhibit apoptosis, but also block autophagy by directly binding to BECN1/Beclin 1. To distinguish whether BCL2, BCL2L1/BCL-XL, or MCL1 influence autophagy directly, or indirectly, through their effects on apoptosis, we compared norma...

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Bibliografiska uppgifter
Huvudupphovsmän: Lindqvist, Lisa M, Vaux, David L
Materialtyp: Artigo
Språk:Inglês
Publicerad: Landes Bioscience 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4203526/
https://ncbi.nlm.nih.gov/pubmed/24991825
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.29639
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