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Synthesis of Unsymmetrical Biphenyls as Potent Cytotoxic Agents
Twenty-six unsymmetrical biphenyls were synthesized and evaluated for cytotoxic activity against DU145, A547, KB and KB-Vin tumor cell lines. Three compounds 27, 35 and 40 showed very potent activity against the HTCL panel with an IC(50) value range of 0.04–3.23 µM. In addition, fourteen active comp...
में बचाया:
| मुख्य लेखकों: | , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2008
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2577197/ https://ncbi.nlm.nih.gov/pubmed/18782668 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.08.050 |
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