Antitumor Agents 255. Novel Glycyrrhetinic Acid-Dehydrozingerone Conjugates as Cytotoxic Agents

Esterification of glycyrrhetinic acid (GA) with dehydrozingerone (DZ) resulted in a novel cytotoxic GA-DZ conjugate. Based on this exciting finding, we conjugated eleven different DZ analogs with GA or other triterpenoids, including oleanoic acid (OA) or ursolic acid (UA). In an in vitro anticancer...

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Hauptverfasser: Tatsuzaki, Jin, Taniguchi, Masahiko, Bastow, Kenneth F., Nakagawa-Goto, Kyoko, Morris-Natschke, Susan L., Itokawa, Hideji, Baba, Kimiye, Lee, Kuo-Hsiung
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034305/
https://ncbi.nlm.nih.gov/pubmed/17591444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2007.06.027
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