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Antitumor Agents. 256. Conjugation of Paclitaxel with Other Antitumor Agents: Evaluation of Novel Conjugates as Cytotoxic Agents
Fifteen different taxoid conjugates were prepared by linking various anticancer compounds, including camptothecin (CPT), epipodophyllotoxin (EP), colchicine (COL), and glycyrrhetinic acid (GA), at the 2’- or 7-position on paclitaxel (TXL, 1) through an ester, imine, amine, or amide bond. Newly synth...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1955431/ https://ncbi.nlm.nih.gov/pubmed/17350834 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.02.051 |
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