Antitumor agents. 258. Syntheses and evaluation of dietary antioxidant – taxoid conjugates as novel cytotoxic agents

Various dietary antioxidants, including vitamins, flavonoids, curcumin, and a coumarin, were conjugated with paclitaxel (1) through an ester linkage. The newly synthesized compounds were evaluated for cytotoxic activity against several human tumor cell lines as well as the corresponding normal cell...

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Hauptverfasser: Nakagawa-Goto, Kyoko, Yamada, Koji, Nakamura, Seikou, Chen, Tzu-Hsuan, Chiang, Po-Cheng, Bastow, Kenneth F., Wang, Shao-Chun, Spohn, Bill, Hung, Mien-Chie, Lee, Fang-Yu, Lee, Fang-Chen, Lee, Kuo-Hsiung
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2329582/
https://ncbi.nlm.nih.gov/pubmed/17643301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.06.083
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