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Antitumor agents. 258. Syntheses and evaluation of dietary antioxidant – taxoid conjugates as novel cytotoxic agents
Various dietary antioxidants, including vitamins, flavonoids, curcumin, and a coumarin, were conjugated with paclitaxel (1) through an ester linkage. The newly synthesized compounds were evaluated for cytotoxic activity against several human tumor cell lines as well as the corresponding normal cell...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2329582/ https://ncbi.nlm.nih.gov/pubmed/17643301 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2007.06.083 |
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