Novel Selective Allosteric Activator of the M(1) Muscarinic Acetylcholine Receptor Regulates Amyloid Processing and Produces Antipsychotic-Like Activity in Rats

Recent studies suggest that subtype-selective activators of M(1)/M(4) muscarinic acetylcholine receptors (mAChRs) may offer a novel approach for the treatment of psychotic symptoms associated with schizophrenia and Alzheimer's disease. Previously developed muscarinic agonists have provided clin...

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Xehetasun bibliografikoak
Egile Nagusiak: Jones, Carrie K., Brady, Ashley E., Davis, Albert A., Xiang, Zixiu, Bubser, Michael, Tantawy, Mohammed Noor, Kane, Alexander S., Bridges, Thomas M., Kennedy, J. Phillip, Bradley, Stefania R., Peterson, Todd E., Ansari, M. Sib, Baldwin, Ronald M., Kessler, Robert M., Deutch, Ariel Y., Lah, James J., Levey, Allan I., Lindsley, Craig W., Conn, P. Jeffrey
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2008
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2577155/
https://ncbi.nlm.nih.gov/pubmed/18842902
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1850-08.2008
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