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Geographically restricted heterogeneity of the Plasmodium falciparum circumsporozoite protein: relevance for vaccine development.

The design of a subunit vaccine against the malaria parasite relies on the epitopes recognized by T cells being identified and polymorphisms therein being defined. Here we present the analysis of a 354-bp fragment of the circumsporozoite (CS) protein encompassing defined proliferative and cytotoxic...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Doolan, D L, Saul, A J, Good, M F
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257683/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1730503/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.2.675-682.1992
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