Probing novel epitopes on the Plasmodium falciparum circumsporozoite protein for vaccine development

Abstract RTS,S and R21 are the only vaccines recommended by the WHO to protect children from Plasmodium falciparum (Pf) clinical malaria. Both vaccines target the Pf sporozoite surface protein circumsporozoite protein (CSP). Recent studies showed that human antibodies neutralize Pf sporozoites most...

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Principais autores:	Pascal S. Krenger, Magali Roques, Anne-Cathrine S. Vogt, Alessandro Pardini, Dominik A. Rothen, Ina Balke, Sophie T. Schnider, Mona O. Mohsen, Volker T. Heussler, Andris Zeltins, Martin F. Bachmann
Formato:	Artigo
Idioma:	Inglês
Publicado:	Nature Portfolio 2024-11-01
Series:	npj Vaccines
Acceso en liña:	https://doi.org/10.1038/s41541-024-01006-8
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