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Probing novel epitopes on the Plasmodium falciparum circumsporozoite protein for vaccine development

Abstract RTS,S and R21 are the only vaccines recommended by the WHO to protect children from Plasmodium falciparum (Pf) clinical malaria. Both vaccines target the Pf sporozoite surface protein circumsporozoite protein (CSP). Recent studies showed that human antibodies neutralize Pf sporozoites most...

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Váldodahkkit: Pascal S. Krenger, Magali Roques, Anne-Cathrine S. Vogt, Alessandro Pardini, Dominik A. Rothen, Ina Balke, Sophie T. Schnider, Mona O. Mohsen, Volker T. Heussler, Andris Zeltins, Martin F. Bachmann
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Nature Portfolio 2024-11-01
Ráidu:npj Vaccines
Liŋkkat:https://doi.org/10.1038/s41541-024-01006-8
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