Inhibition of the p53 E3 Ligase HDM-2 Induces Apoptosis and DNA Damage-Independent p53 Phosphorylation in Mantle Cell Lymphoma

Lignende værker

• HDM-2 inhibition suppresses expression of ribonucleotide reductase subunit M2, and synergistically enhances gemcitabine-induced cytotoxicity in mantle cell lymphoma
  af: Jones, Richard J., et al.
  Udgivet: (2011)
• A Regulatory Loop Composed of RAP80-HDM2-p53 Provides RAP80-enhanced p53 Degradation by HDM2 in Response to DNA Damage
  af: Yan, Jun, et al.
  Udgivet: (2009)
• Modulation of p73 isoforms expression induces anti-proliferative and pro-apoptotic activity in mantle cell lymphoma independent of p53 status
  af: Hassan, Hesham M., et al.
  Udgivet: (2016)
• HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
  af: Linares, Laëtitia K., et al.
  Udgivet: (2003)
• p53 is associated with high‐risk and pinpoints TP53 missense mutations in mantle cell lymphoma
  af: Rodrigues, Joana M., et al.
  Udgivet: (2020)