p53 is associated with high‐risk and pinpoints TP53 missense mutations in mantle cell lymphoma

Survival for patients diagnosed with mantle cell lymphoma (MCL) has improved drastically in recent years. However, patients carrying mutations in tumour protein p53 (TP53) do not benefit from modern chemotherapy‐based treatments and have poor prognosis. Thus, there is a clinical need to identify mis...

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Dettagli Bibliografici
Pubblicato in:Br J Haematol
Autori principali: Rodrigues, Joana M., Hassan, May, Freiburghaus, Catja, Eskelund, Christian W., Geisler, Christian, Räty, Riikka, Kolstad, Arne, Sundström, Christer, Glimelius, Ingrid, Grønbæk, Kirsten, Kwiecinska, Anna, Porwit, Anna, Jerkeman, Mats, Ek, Sara
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Haematological Malignancy – Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754513/
https://ncbi.nlm.nih.gov/pubmed/32748433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.17023
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