p53 is associated with high‐risk and pinpoints TP53 missense mutations in mantle cell lymphoma

Survival for patients diagnosed with mantle cell lymphoma (MCL) has improved drastically in recent years. However, patients carrying mutations in tumour protein p53 (TP53) do not benefit from modern chemotherapy‐based treatments and have poor prognosis. Thus, there is a clinical need to identify mis...

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Detalhes bibliográficos
Publicado no:Br J Haematol
Main Authors: Rodrigues, Joana M., Hassan, May, Freiburghaus, Catja, Eskelund, Christian W., Geisler, Christian, Räty, Riikka, Kolstad, Arne, Sundström, Christer, Glimelius, Ingrid, Grønbæk, Kirsten, Kwiecinska, Anna, Porwit, Anna, Jerkeman, Mats, Ek, Sara
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Haematological Malignancy – Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7754513/
https://ncbi.nlm.nih.gov/pubmed/32748433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.17023
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