Loading...
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
The RING finger proteins HdmX and Hdm2 share significant structural and functional similarity. Hdm2 is a member of the RING finger family of ubiquitin-protein ligases E3 and targets the tumor suppressor protein p53 for degradation. Although HdmX also binds to p53, HdmX does not induce p53 degradatio...
Na minha lista:
| Main Authors: | , , , , |
|---|---|
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2003
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC218704/ https://ncbi.nlm.nih.gov/pubmed/14507994 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2030930100 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|