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Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation
Acetylation is a prominent post-translational modification of nucleosomal histone N-terminal tails, which regulates chromatin accessibility. Accordingly, histone acetyltransferases (HATs) play major roles in processes such as transcription. Here, we show that the HAT Tip60, which is involved in DNA...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125958/ https://ncbi.nlm.nih.gov/pubmed/11927554 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/21.7.1704 |
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