Tip60 is targeted to proteasome-mediated degradation by Mdm2 and accumulates after UV irradiation

Acetylation is a prominent post-translational modification of nucleosomal histone N-terminal tails, which regulates chromatin accessibility. Accordingly, histone acetyltransferases (HATs) play major roles in processes such as transcription. Here, we show that the HAT Tip60, which is involved in DNA...

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Bibliografiske detaljer

Udgivet i:	EMBO J
Principais autores:	Legube, Gaëlle, Linares, Laetitia K., Lemercier, Claudie, Scheffner, Martin, Khochbin, Saadi, Trouche, Didier
Format:	Artigo
Sprog:	Inglês
Udgivet:	Nature Publishing Group 2002
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125958/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11927554/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/21.7.1704
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