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Molecular Mechanism of Ion-Ion and Ion-Substrate Coupling in the Na(+)-Dependent Leucine Transporter LeuT

Ion-coupled transport of neurotransmitter molecules by neurotransmitter:sodium symporters (NSS) play an important role in the regulation of neuronal signaling. One of the major events in the transport cycle is ion-substrate coupling and formation of the high-affinity occluded state with bound ions a...

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Autori principali: Caplan, David A., Subbotina, Julia O., Noskov, Sergei Yu
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576368/
https://ncbi.nlm.nih.gov/pubmed/18708457
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.139741
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