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Molecular Mechanism of Ion-Ion and Ion-Substrate Coupling in the Na(+)-Dependent Leucine Transporter LeuT
Ion-coupled transport of neurotransmitter molecules by neurotransmitter:sodium symporters (NSS) play an important role in the regulation of neuronal signaling. One of the major events in the transport cycle is ion-substrate coupling and formation of the high-affinity occluded state with bound ions a...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The Biophysical Society
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2576368/ https://ncbi.nlm.nih.gov/pubmed/18708457 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.108.139741 |
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