Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT

The coupled transport of ions and substrates allows transporters to accumulate substrates using the energy of transmembrane ion gradients and electrical potentials. During transport, conformational changes that switch accessibility of substrate and ion binding sites from one side of the membrane to...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Zhang, Yuan-Wei, Tavoulari, Sotiria, Sinning, Steffen, Aleksandrova, Antoniya A., Forrest, Lucy R., Rudnick, Gary
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2018
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156673/
https://ncbi.nlm.nih.gov/pubmed/30181291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716870115
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