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Structural elements required for coupling ion and substrate transport in the neurotransmitter transporter homolog LeuT

The coupled transport of ions and substrates allows transporters to accumulate substrates using the energy of transmembrane ion gradients and electrical potentials. During transport, conformational changes that switch accessibility of substrate and ion binding sites from one side of the membrane to...

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Foilsithe in:Proc Natl Acad Sci U S A
Main Authors: Zhang, Yuan-Wei, Tavoulari, Sotiria, Sinning, Steffen, Aleksandrova, Antoniya A., Forrest, Lucy R., Rudnick, Gary
Formáid: Artigo
Teanga:Inglês
Foilsithe: National Academy of Sciences 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156673/
https://ncbi.nlm.nih.gov/pubmed/30181291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716870115
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