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TRPV4 mediates hypotonicity-induced ATP release by the thick ascending limb

Extracellular ATP is an autocrine/paracrine factor that regulates renal function. Transient receptor potential vanilloid (TRPV) 4 is a cation channel that mediates release of autocrine/paracrine factors by acting as an osmosensor. The renal medulla, and therefore the thick ascending limb, is exposed...

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Bibliografiske detaljer
Main Authors: Silva, Guillermo B., Garvin, Jeffrey L.
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576139/
https://ncbi.nlm.nih.gov/pubmed/18684885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90365.2008
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