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TRPV4 mediates flow-induced increases in intracellular Ca in medullary thick ascending limbs
Medullary thick ascending limbs (mTAL) regulate Na balance and therefore blood pressure. We previously showed that cell swelling and luminal flow activates the mechano-sensitive channel TRPV4 in mTAL. AIM: We hypothesized that TRPV4 mediates flow-induced increases in intracellular Ca (Cai) in rat mT...
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| Udgivet i: | Acta Physiol (Oxf) |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5406130/ https://ncbi.nlm.nih.gov/pubmed/25980432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/apha.12528 |
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