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TRPV4 activation mediates flow-induced nitric oxide production in the rat thick ascending limb
Nitric oxide (NO) regulates renal function. Luminal flow stimulates NO production in the thick ascending limb (TAL). Transient receptor potential vanilloid 4 (TRPV4) is a mechano-sensitive channel activated by luminal flow in different types of cells. We hypothesized that TRPV4 mediates flow-induced...
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| Главные авторы: | , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Physiological Society
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4166729/ https://ncbi.nlm.nih.gov/pubmed/24966090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00619.2013 |
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