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TRPV4 activation mediates flow-induced nitric oxide production in the rat thick ascending limb

Nitric oxide (NO) regulates renal function. Luminal flow stimulates NO production in the thick ascending limb (TAL). Transient receptor potential vanilloid 4 (TRPV4) is a mechano-sensitive channel activated by luminal flow in different types of cells. We hypothesized that TRPV4 mediates flow-induced...

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Библиографические подробности
Главные авторы: Cabral, Pablo D., Garvin, Jeffrey L.
Формат: Artigo
Язык:Inglês
Опубликовано: American Physiological Society 2014
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166729/
https://ncbi.nlm.nih.gov/pubmed/24966090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00619.2013
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