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TRPV4 activation mediates flow-induced nitric oxide production in the rat thick ascending limb

Nitric oxide (NO) regulates renal function. Luminal flow stimulates NO production in the thick ascending limb (TAL). Transient receptor potential vanilloid 4 (TRPV4) is a mechano-sensitive channel activated by luminal flow in different types of cells. We hypothesized that TRPV4 mediates flow-induced...

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Detaylı Bibliyografya
Asıl Yazarlar: Cabral, Pablo D., Garvin, Jeffrey L.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166729/
https://ncbi.nlm.nih.gov/pubmed/24966090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00619.2013
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