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TRPV4 activation mediates flow-induced nitric oxide production in the rat thick ascending limb

Nitric oxide (NO) regulates renal function. Luminal flow stimulates NO production in the thick ascending limb (TAL). Transient receptor potential vanilloid 4 (TRPV4) is a mechano-sensitive channel activated by luminal flow in different types of cells. We hypothesized that TRPV4 mediates flow-induced...

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Detalhes bibliográficos
Main Authors: Cabral, Pablo D., Garvin, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166729/
https://ncbi.nlm.nih.gov/pubmed/24966090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00619.2013
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