Loading...

TRPV4 activation mediates flow-induced nitric oxide production in the rat thick ascending limb

Nitric oxide (NO) regulates renal function. Luminal flow stimulates NO production in the thick ascending limb (TAL). Transient receptor potential vanilloid 4 (TRPV4) is a mechano-sensitive channel activated by luminal flow in different types of cells. We hypothesized that TRPV4 mediates flow-induced...

Full description

Saved in:
Bibliographic Details
Main Authors: Cabral, Pablo D., Garvin, Jeffrey L.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4166729/
https://ncbi.nlm.nih.gov/pubmed/24966090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00619.2013
Tags: Add Tag
No Tags, Be the first to tag this record!