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Rac1 mediates NaCl-induced superoxide generation in the thick ascending limb
Superoxide (O(2)(−)) produced by NADPH oxidase regulates Na absorption and renal hemodynamics. Increased NaCl in the thick ascending limb (TAL) stimulates O(2)(−) generation. However, we do not know whether physiological changes in NaCl concentration augment O(2)(−) generation, nor do we know the me...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Physiological Society
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2822510/ https://ncbi.nlm.nih.gov/pubmed/19923407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00472.2009 |
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