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Akt1 mediates purinergic-dependent NOS3 activation in thick ascending limbs

Extracellular ATP regulates many physiological processes via release of nitric oxide (NO). ATP stimulates NO in thick ascending limbs (TALs), but the signaling cascade involved in the cells of this nephron segment, as well as many other types of cells, is poorly understood. We hypothesized that ATP...

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Detalles Bibliográficos
Main Authors: Silva, Guillermo B., Garvin, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado: American Physiological Society 2009
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739713/
https://ncbi.nlm.nih.gov/pubmed/19570880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00270.2009
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