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Akt1 mediates purinergic-dependent NOS3 activation in thick ascending limbs

Extracellular ATP regulates many physiological processes via release of nitric oxide (NO). ATP stimulates NO in thick ascending limbs (TALs), but the signaling cascade involved in the cells of this nephron segment, as well as many other types of cells, is poorly understood. We hypothesized that ATP...

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Détails bibliographiques
Auteurs principaux: Silva, Guillermo B., Garvin, Jeffrey L.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2739713/
https://ncbi.nlm.nih.gov/pubmed/19570880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00270.2009
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