FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells

Fas-associated death domain protein (FADD) and caspase-8 (casp8) are vital intermediaries in apoptotic signaling induced by tumor necrosis factor family ligands. Paradoxically, lymphocytes lacking FADD or casp8 fail to undergo normal clonal expansion following antigen receptor cross-linking and succ...

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Autori principali: Bell, Bryan D., Leverrier, Sabrina, Weist, Brian M., Newton, Ryan H., Arechiga, Adrian F., Luhrs, Keith A., Morrissette, Naomi S., Walsh, Craig M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2008
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2575479/
https://ncbi.nlm.nih.gov/pubmed/18946037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808597105
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