Caspase-8-dependent inflammatory responses are controlled by its adapter, FADD, and necroptosis

Cell death pathways regulate various homeostatic processes. Autoimmune lymphoproliferative syndrome (ALPS) in humans and Lymphoproliferative (LPR) disease in mice are a result of abrogated CD95-induced apoptosis. Because Caspase-8 mediates CD95 signaling, we applied genetic approaches to dissect the...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Immunity
Egile Nagusiak: Tummers, Bart, Mari, Luigi, Guy, Clifford S., Heckmann, Bradlee L., Rodriguez, Diego A., Rühl, Sebastian, Moretti, Julien, Crawford, Jeremy Chase, Fitzgerald, Patrick, Kanneganti, Thirumala-Devi, Janke, Laura J., Pelletier, Stephane, Blander, J. Magarian, Green, Douglas R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7306001/
https://ncbi.nlm.nih.gov/pubmed/32428502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2020.04.010
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