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Atomic detail of chemical transformation at the transition state of an enzymatic reaction
Transition path sampling (TPS) has been applied to the chemical step of human purine nucleoside phosphorylase (PNP). The transition path ensemble provides insight into the detailed mechanistic dynamics and atomic motion involved in transition state passage. The reaction mechanism involves early loss...
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| Asıl Yazarlar: | , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
2008
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2575456/ https://ncbi.nlm.nih.gov/pubmed/18946041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808413105 |
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